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KMID : 0383820120720030323
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Tuberculosis and Respiratory Diseases
2012 Volume.72 No. 3 p.323 ~ p.327
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A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis
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Kang Shin-Myung
Jang Young-Rock
Yoon Hyun-Hwa
Kim Su-Ji
Kim Eun-Young
Ha Seung-Yeon
Park Jeong-Woong
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Abstract
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5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symptoms and multiple pulmonary nodules from a chest radiography that was pathologically diagnosed with a limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. To our knowledge, this is the first report of a balsalazide-induced limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant.
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KEYWORD
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Balsalazide, Wegener Granulomatosis, Colitis, Ulcerative
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